For some biochemical reason I have found my adult percecption of things on the depressed side. For many years now I have taken SAMe and have found a minimum dose of 400 mg every other night seems to keep me even and on the more positive side. When I completely go off it , I call it the" gray wash " view of life returns so there does appear to be something it does chemistry wise to improve . I tried a couple of other brands that iHerb carries, and they worked fine but I prefer Nutralife for some reason. I always balence this product with Homocystine Modulators and lately TMJ as I understand this is important.

I have been using Doctor's Best SAM-e 400 for a few years now . It is very good for mild depression and my joints love it too .